Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.82 |
| ▸ | PIK3CD | O00329 | 19/20 | 0.82 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.79 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9276725 | 0.92 | PIK3CG (0.83) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2783009 | 0.89 | PIK3CG (0.84) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL844931 | 0.89 | PIK3CG (0.77) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL860441 | 0.88 | PIK3CG (0.64) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3347225 | 0.87 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2781519 | 0.86 | PIK3CG (0.86) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2781870 | 0.86 | PIK3CG (0.84) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3098954 | 0.86 | PIK3CG (0.82) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2762514 | 0.85 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CBPIK3CA | |
| SCHEMBL2762276 | 0.84 | PIK3CG (0.98) | PIK3CGPIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367830-B2 | Methods for the identification of phosphatidylinositol kinase interacting molecules and for the purification of phosphatidylinositol kinase proteins | CELLZOME AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-8367830-B2 | Methods for the identification of phosphatidylinositol kinase interacting molecules and for the purification of phosphatidylinositol kinase proteins | CELLZOME AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-8367830-B2 | Methods for the identification of phosphatidylinositol kinase interacting molecules and for the purification of phosphatidylinositol kinase proteins | CELLZOME AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20120135421-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2012-05-31 | — | — | US | disclosed |
| US-20120135421-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2012-05-31 | — | — | US | disclosed |
| US-20120135421-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2012-05-31 | — | — | US | disclosed |
| EP-2432782-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133318-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133318-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | CELLZOME AG (DE) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135421-A1 | METHODS FOR THE IDENTIFICATION OF PHOSPHATIDYLINOSITOL KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF PHOSPHATIDYLINOSITOL KINASE PROTEINS | PIP4K2B, PIP4K2C, PI4KB | PIK3CG 18/4885PIK3CD 17/4885PIK3CB 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.