Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456323 | 0.89 | ESR2 (0.33) | CYP3A4ESR2ESR1CYP2C9DGAT1 | |
| SCHEMBL9479362 | 0.89 | CYP17A1 (0.35) | CYP17A1CYP11B2CYP11B1CYP3A4ESR2 | |
| SCHEMBL9479375 | 0.89 | CYP17A1 (0.35) | CYP17A1CYP11B2CYP11B1CYP3A4ESR2 | |
| SCHEMBL9479351 | 0.89 | CYP17A1 (0.35) | CYP17A1CYP11B2CYP11B1CYP3A4ESR2 | |
| SCHEMBL9479369 | 0.89 | CYP17A1 (0.35) | CYP17A1CYP11B2CYP11B1CYP3A4ESR2 | |
| SCHEMBL8452111 | 0.88 | DGAT1 (0.33) | CYP11B2CYP11B1CYP3A4ESR2ESR1 | |
| SCHEMBL8447865 | 0.87 | ESR2 (0.31) | CYP3A4ESR2ESR1CYP2C9DGAT1 | |
| SCHEMBL8448059 | 0.87 | DGAT1 (0.32) | CYP3A4ESR2ESR1CYP2C9DGAT1 | |
| SCHEMBL8380306 | 0.86 | CYP3A4 (0.33) | CYP17A1CYP11B2CYP11B1CYP3A4ESR2 | |
| SCHEMBL8447729 | 0.86 | ESR2 (0.36) | CYP3A4ESR2ESR1CYP2C9DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |