Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446468 | 0.97 | MME (0.51) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8451289 | 0.97 | MME (0.52) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8452236 | 0.95 | MME (0.53) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8446417 | 0.93 | MME (0.52) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8451858 | 0.93 | MME (0.55) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL7568216 | 0.92 | MME (0.62) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8448662 | 0.91 | MME (0.57) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8453223 | 0.90 | MME (0.52) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL7572812 | 0.90 | MME (0.61) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8447122 | 0.89 | MME (0.57) | MMEACEMMP3CTSBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |