Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450544 | 0.94 | ACE (0.48) | ACEPPARGPPARAMMEFOLH1 | |
| SCHEMBL8451005 | 0.90 | ACE (0.49) | ACEMMP9PPARGPPARAMME | |
| SCHEMBL8451692 | 0.85 | ACE (0.56) | ACE | |
| SCHEMBL8450411 | 0.83 | PPARA (0.41) | ACEMMP3MMP1MMP8MMP9 | |
| SCHEMBL6576249 | 0.82 | MME (0.45) | ACEMMP9PPARGPPARAMME | |
| SCHEMBL6576254 | 0.82 | MME (0.45) | ACEMMP9PPARGPPARAMME | |
| SCHEMBL8452662 | 0.81 | ACE (0.58) | ACE | |
| SCHEMBL8451271 | 0.81 | ACE (0.51) | ACEMMP9PPARGPPARAMME | |
| SCHEMBL6574206 | 0.80 | ACE (0.70) | ACE | |
| SCHEMBL6575444 | 0.80 | ACE (0.70) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |