Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576249 | 0.92 | MME (0.45) | ACEPPARAMMEPPARGFOLH1 | |
| SCHEMBL6576254 | 0.92 | MME (0.45) | ACEPPARAMMEPPARGFOLH1 | |
| SCHEMBL8451005 | 0.90 | ACE (0.49) | ACEPPARAMMEPPARGFOLH1 | |
| SCHEMBL8452123 | 0.85 | ACE (0.71) | ACE | |
| SCHEMBL8450544 | 0.83 | ACE (0.48) | ACEPPARAMMEPPARGFOLH1 | |
| SCHEMBL8446657 | 0.82 | PPARA (0.49) | ACEPPARAMMEPPARGL3MBTL1 | |
| SCHEMBL8451023 | 0.82 | MME (0.45) | ACEPPARAMMEPPARGL3MBTL1 | |
| SCHEMBL8449644 | 0.81 | ACE (0.46) | ACEPPARAMMEPPARGFOLH1 | |
| SCHEMBL8451673 | 0.76 | ACE (0.59) | ACE | |
| SCHEMBL6578424 | 0.76 | ACE (0.59) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |