Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733640 | 0.82 | MAOB (0.47) | HPGDLMNACA1CA2AR | |
| SCHEMBL3971294 | 0.79 | FGFR1 (0.43) | HPGDLMNAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL379017 | 0.78 | MAOB (0.49) | HPGDLMNACA12CA9AR | |
| SCHEMBL378950 | 0.78 | MAOB (0.49) | HPGDLMNACA12CA9AR | |
| SCHEMBL7991854 | 0.76 | CA1 (0.56) | HPGDLMNACA1CA2CA12 | |
| SCHEMBL7991858 | 0.76 | CA1 (0.56) | HPGDLMNACA1CA2CA12 | |
| SCHEMBL8450259 | 0.74 | HPGD (0.50) | HPGDLMNACA1CA2CA12 | |
| SCHEMBL19230688 | 0.72 | MEN1 (0.50) | HPGDLMNAPTPN1ALDH1A1MEN1 | |
| SCHEMBL379015 | 0.72 | ERN1 (0.48) | ERN1F10ALDH1A1MAPTKDM4E | |
| SCHEMBL379016 | 0.72 | ERN1 (0.48) | ERN1F10ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064379-A2 | BIOMIMETIC COMBINATORIAL SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-12-16 | — | — | WO | disclosed |