Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379016 | 1.00 | ERN1 (0.48) | ERN1MRGPRX4MCL1FFAR4F9 | |
| SCHEMBL378950 | 0.77 | MAOB (0.49) | ERN1MAOBHSP90AA1MAPTMAPK1 | |
| SCHEMBL379017 | 0.77 | MAOB (0.49) | ERN1MAOBHSP90AA1MAPTMAPK1 | |
| SCHEMBL12635750 | 0.76 | PTGER1 (0.46) | ERN1MRGPRX4FFAR4MAPTMAPK1 | |
| SCHEMBL7346174 | 0.73 | MRGPRX4 (0.64) | ERN1MRGPRX4MCL1F9F10 | |
| SCHEMBL379281 | 0.73 | MAOB (0.67) | MRGPRX4FFAR4NR4A2MAOAMAOB | |
| SCHEMBL8450255 | 0.72 | HPGD (0.49) | ERN1F10KDM4EALDH1A1MAPT | |
| SCHEMBL2137838 | 0.72 | MRGPRX4 (0.69) | MRGPRX4HDAC4NR4A2MAOAMAOB | |
| SCHEMBL16346074 | 0.70 | GSTP1 (0.66) | MRGPRX4MCL1FFAR4HDAC4NR4A2 | |
| SCHEMBL7046152 | 0.69 | MAOB (0.56) | MCL1MAOAMAOBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8313669-B2 | Liquid-crystal display | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-11-20 | — | — | US | disclosed |
| EP-2181174-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-01-25 | — | — | EP | disclosed |
| US-20110101269-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2181174-A1 | LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009030322-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110101269-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, LPXN, PSAP | ERN1 4101/4885MRGPRX4 3808/4885MCL1 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.