Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194100 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1NPSR1ALOX5PTGS1 | |
| SCHEMBL8455303 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1NPSR1ALOX5PTGS1 | |
| SCHEMBL1684995 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1NPSR1ALOX5PTGS1 | |
| SCHEMBL8577780 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1NPSR1ALOX5PTGS1 | |
| Flucythrinate SCHEMBL3514253 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 | |
| Flucythrinate SCHEMBL30014944 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 | |
| Flucythrinate SCHEMBL54722 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 | |
| Flucythrinate SCHEMBL29484439 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 | |
| Flucythrinate SCHEMBL682196 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 | |
| Flucythrinate SCHEMBL10617509 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TDP1ALOX5PTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886207-A | INSECTICIDES, MITICIDES | SHANGHAI ZHONGXI PHARMACEUTICAL CO. LTD. (CN) | 1999-03-23 | — | — | US | claimed |
| EP-0687670-A1 | AN OPTICALLY ACTIVE COMPOUND OF FLUBROCYTHRINATE, A PROCESS FOR PREPARING THE SAME AND ITS USE | Shanghai Zhongxi Pharmaceutical Co. Ltd. (CN) | 1995-12-20 | — | — | EP | claimed |
| US-5886207-A | INSECTICIDES, MITICIDES | SHANGHAI ZHONGXI PHARMACEUTICAL CO. LTD. (CN) | 1999-03-23 | — | — | US | disclosed |