Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569380 | 0.95 | ACE (0.52) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7569374 | 0.95 | ACE (0.52) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL8450193 | 0.88 | TACR1 (0.52) | MMEACETACR1ALDH1A1MAPT | |
| SCHEMBL8447122 | 0.87 | MME (0.57) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8450243 | 0.87 | MME (0.57) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8451268 | 0.87 | MME (0.46) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL27446786 | 0.86 | ACE (0.51) | MMEACETACR1ALDH1A1MAPT | |
| SCHEMBL8450818 | 0.85 | MME (0.40) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL8446494 | 0.84 | MME (0.53) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8451243 | 0.84 | MME (0.53) | MMEACETACR1CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |