Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450197 | 0.89 | UTS2R (0.42) | CTSLOPRK1OPRM1OPRD1CTSB | |
| SCHEMBL8450247 | 0.89 | MME (0.47) | MMEFDFT1ACECPA1ACE2 | |
| SCHEMBL8451272 | 0.88 | PTGES (0.39) | MMEFDFT1ACECPA1ACE2 | |
| SCHEMBL7569380 | 0.86 | ACE (0.52) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7569374 | 0.86 | ACE (0.52) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL8450814 | 0.85 | MME (0.46) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL8450113 | 0.83 | MME (0.43) | MMEACEMMP3CTSBLNPEP | |
| SCHEMBL8446495 | 0.81 | MME (0.43) | MMEACEMMP3CTSBCTSK | |
| SCHEMBL8451246 | 0.81 | MME (0.47) | MMEFDFT1ACECPA1ACE2 | |
| SCHEMBL8453092 | 0.81 | MME (0.43) | MMEACEACE2MMP3CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |