Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.60 |
| ▸ | NOS3 | P29474 | 5/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619794 | 0.92 | NOS1 (0.72) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL8575520 | 0.91 | NOS1 (0.62) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL7157648 | 0.89 | NOS1 (0.58) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6620863 | 0.85 | NOS1 (0.83) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6621035 | 0.84 | NOS1 (0.72) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6621913 | 0.84 | NOS1 (0.65) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27594386 | 0.84 | NOS1 (0.49) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6620835 | 0.81 | NOS1 (0.74) | NOS1NOS3CHRM2CHRM4 | |
| SCHEMBL27549067 | 0.81 | NOS1 (0.44) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6623791 | 0.80 | NOS1 (0.68) | NOS1NOS3CHRM2CHRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891332-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036871-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1997-10-09 | — | — | WO | disclosed |