Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.46 |
| ▸ | ACE | P12821 | 6/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450803 | 0.89 | MME (0.48) | MMEACECTSBPSMB5CTSL | |
| SCHEMBL8453149 | 0.86 | MME (0.47) | MMEACECTSBCYP26A1CTSL | |
| SCHEMBL8446471 | 0.84 | MME (0.47) | MMEACECTSBCTSL | |
| SCHEMBL7573777 | 0.82 | MME (0.68) | MMEACECTSBCTSLCTSS | |
| SCHEMBL7573782 | 0.82 | MME (0.68) | MMEACECTSBCTSLCTSS | |
| SCHEMBL8446405 | 0.82 | MME (0.48) | MMEACECTSBPPARGPPARA | |
| SCHEMBL8446482 | 0.81 | MME (0.49) | MMEACECTSBUTS2RCYP2D6 | |
| SCHEMBL8450834 | 0.81 | MME (0.61) | MMEACECTSBCTSLCTSS | |
| SCHEMBL8450113 | 0.81 | MME (0.43) | MMEACECTSBUTS2RPTGES | |
| SCHEMBL8446449 | 0.81 | MME (0.47) | MMEACECTSBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |