SCHEMBL8450940

SCHEMBL8450940

CCCC1COC(c2cc(F)c(C(=O)Oc3ccc(F)c(F)c3)c(F)c2)OC1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 1/20 0.32
DRD2 P14416 2/20 0.31
ADRA1A P35348 2/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15695413 0.89
SCHEMBL17035812 0.87 FFAR4 (0.32)
SCHEMBL35739365 0.87 FFAR4 (0.32)
SCHEMBL19829129 0.85
SCHEMBL24311309 0.84
SCHEMBL18310553 0.84 FFAR4 (0.32)
SCHEMBL27006304 0.83 DHODH (0.38) MAPTCYP2C9
SCHEMBL27006323 0.83
SCHEMBL15695410 0.81 FFAR4 (0.31)
SCHEMBL15695412 0.80 RARA (0.34) MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175222-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2015-11-03 US disclosed
US-9175222-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2015-11-03 US disclosed
US-20140132868-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20140132868-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-5858272-A HAVING A LARGE .DELTA..EPSILON. WHILE MAINTAINING A HIGH VOLTAGE HOLDING RATIO; DRIVING THIN FILM TRANSISTOR AT LOW VOLTAGE; EXCELLANT COMPATIBILITY WITH CONVENTIONAL LIQUID CRYSALS; RELIABILITY CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0819685-A1 Phenyldioxane derivatives, liquid crystal compositions, and liquid crystal display elements Chisso Corporation (JP) 1998-01-21 EP disclosed