Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83919 | 1.00 | CNR2 (0.42) | CNR2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL84512 | 1.00 | CNR2 (0.42) | CNR2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16382029 | 0.93 | OGA (0.39) | CNR2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12797832 | 0.87 | LMNA (0.36) | CNR2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25142073 | 0.83 | HRH4 (0.43) | ALDH1A1SMN1; SMN2OGALMNAHTT | |
| SCHEMBL16517601 | 0.81 | KMT2A (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3390844 | 0.81 | PTPN11 (0.38) | OGAKMT2AHTTPSEN1PSEN2 | |
| SCHEMBL16517600 | 0.81 | KMT2A (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22796061 | 0.81 | MAP4K4 (0.49) | NPC1ALDH1A1RAB9ANPSR1MAPT | |
| SCHEMBL82706 | 0.79 | HRH4 (0.36) | OGAKMT2AHTTHRH4PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129526-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7973028-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7968537-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1622879-B1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITIONS CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-7928110-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1622879-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099160-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | C5, C1S, TYMS | CNR2 298/4885NPC1 3323/4885ALDH1A1 2802/4885 |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CNR2 516/4885NPC1 3589/4885ALDH1A1 2192/4885 |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CNR2 501/4885NPC1 3599/4885ALDH1A1 2186/4885 |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, CCNB3 | CNR2 369/4885NPC1 3341/4885ALDH1A1 3306/4885 |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CNR2 521/4885NPC1 3626/4885ALDH1A1 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.