⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL866238 | 0.97 | — | — | |
| SCHEMBL12503514 | 0.88 | — | — | |
| SCHEMBL1822519 | 0.81 | — | — | |
| SCHEMBL6057337 | 0.74 | — | — | |
| SCHEMBL30843815 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL5862089 | 0.71 | — | — | |
| SCHEMBL28676517 | 0.71 | — | — | |
| Ether SCHEMBL8434557 | 0.71 | — | — | |
| SCHEMBL3390758 | 0.69 | — | — | |
| SCHEMBL514355 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063500-A | Preparation method of (2S, 5S) -5-hydroxy piperidine-2-formic acid | 浙江九洲药业股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117720526-A | STING agonist and preparation and application thereof | 威海纽兰生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117623925-A | Method for deoxidizing and converting photocatalytic alcohol | 同济大学 | 2024-03-01 | — | — | CN | claimed |
| WO-2024002205-A1 | BIFUNCTIONAL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE BIFUNCTIONAL COMPOUND, AND METHOD FOR TREATING ANDROGEN RECEPTOR RELATED DISEASE BY USING THE SAME | ANHORN MEDICINES CO., LTD. (CN) | 2024-01-04 | — | — | WO | claimed |
| WO-2024002289-A1 | PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE | ANHORN MEDICINES CO., LTD. (CN) | 2024-01-04 | — | — | WO | claimed |
| WO-2024002206-A1 | BIFUNCTIONAL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE BIFUNCTIONAL COMPOUND, AND METHOD FOR TREATING ANDROGEN RECEPTOR RELATED DISEASES BY USING THE SAME | ANHORN MEDICINES CO., LTD. (CN) | 2024-01-04 | — | — | WO | claimed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| EP-4277903-A1 | PROCESS FOR PREPARING (S)-1-(1-ACRYLOYLPYRROLIDIN-3-YL)-3-((3,5-DIMETHOXYPHENYL) ETHYNYL)-5-(METHYLAMINO)-1H-PYRAZOLE-4-CARBOXAMIDE | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2023-11-22 | — | — | EP | claimed |
| WO-2016173425-A1 | A GLUCOPYRANOSYL DERIVATIVE AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-11-03 | — | — | WO | claimed |
| WO-2015043473-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | claimed |
| EP-2470502-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | Novartis AG (CH) | 2012-07-04 | — | — | EP | claimed |
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2012-06-14 | — | — | US | claimed |
| WO-2011023677-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2011-03-03 | — | — | WO | claimed |
| US-7232912-B2 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation | AGOURON PHARMACEUTICALS, INC. (US) | 2007-06-19 | — | — | US | claimed |
| US-20060111322-A1 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation | AGOURON PHARMACEUTICALS, INC. | 2006-05-25 | — | — | US | claimed |
| US-6919461-B2 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation | AGOURON PHARMACEUTICALS, INC. (US) | 2005-07-19 | — | — | US | claimed |
| US-6891044-B2 | Indazole compounds and pharmaceutical compositions for Inhibiting protein kinases, and methods for their use | AGOURON PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | claimed |
| US-20040220248-A1 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | KANIA ROBERT STEVEN (US) | 2004-11-04 | — | — | US | claimed |