Lodenosine

Lodenosine

SCHEMBL8451244

Nc1ncnc2c1ncn2[C@H]1O[C@H](CO)C[C@@H]1F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.61
ERBB2 P04626 1/20 0.61
ADORA3 P0DMS8 4/20 0.59
ADORA2B P29275 3/20 0.59
ADORA2A P29274 2/20 0.59
ADORA1 P30542 2/20 0.59
PI4KA P42356 2/20 0.59
PI4K2B Q8TCG2 2/20 0.59
PI4K2A Q9BTU6 2/20 0.59
PI4KB Q9UBF8 2/20 0.59
DPP4 P27487 1/20 0.59
MEN1 O00255 1/20 0.59
SLC28A1 O00337 1/20 0.59
MAP3K7 O43318 1/20 0.59
SLC28A2 O43868 1/20 0.59
GAPDH P04406 1/20 0.59
MAPK1 P28482 1/20 0.59
STAT6 P42226 1/20 0.59
KMT2A Q03164 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lodenosine SCHEMBL3482 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL16670086 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL29663669 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL29831913 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL3483 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL29421139 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL29329162 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL30998176 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL22869478 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A
Lodenosine SCHEMBL97908 1.00 EGFR (0.61) EGFRERBB2ADORA3ADORA2BADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999038879-A1 PROCESS FOR PRODUCING NUCLEOSIDE DERIVATIVES AJINOMOTO CO., INC. (JP) 1999-08-05 WO disclosed