SCHEMBL8451900

SCHEMBL8451900

Cc1ccc(CCC2CCC(CCc3ccc(CCc4ccc(Cl)c(F)c4)cc3)CC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
PROKR1 Q8TCW9 3/20 0.38
FPR2 P25090 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CCR3 P51677 1/20 0.35
DRD4 P21917 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
DRD3 P35462 1/20 0.34
C3AR1 Q16581 1/20 0.34
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8451894 1.00 MAOB (0.44) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8453562 0.94 MAOB (0.40) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8454668 0.94 MAOB (0.40) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8453568 0.94 MAOB (0.40) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8454671 0.94 MAOB (0.40) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8452805 0.92 MAOB (0.39) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8452803 0.92 MAOB (0.39) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8451888 0.89 MAOB (0.42) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8451886 0.89 MAOB (0.42) MAOBSLC6A2SLC6A4SLC6A3PROKR1
SCHEMBL8447396 0.89 MAOB (0.38) MAOBSLC6A2SLC6A4SLC6A3PROKR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858275-A Chlorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0785179-A1 CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1997-07-23 EP disclosed