Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447399 | 1.00 | MAOB (0.38) | MAOBSLC6A2SLC6A4SLC6A3PTGES2 | |
| SCHEMBL8454601 | 0.92 | CYP3A4 (0.35) | MAOBSLC6A2SLC6A4SLC6A3PTGES2 | |
| SCHEMBL8454595 | 0.92 | CYP3A4 (0.35) | MAOBSLC6A2SLC6A4SLC6A3PTGES2 | |
| SCHEMBL8453499 | 0.91 | MAOA (0.38) | MAOBGPR84PROKR1FPR2CHKA | |
| SCHEMBL8452670 | 0.91 | CYP11B1 (0.35) | GPR84PROKR1FPR2CHKACYP11B1 | |
| SCHEMBL8452674 | 0.91 | CYP11B1 (0.35) | GPR84PROKR1FPR2CHKACYP11B1 | |
| SCHEMBL8453505 | 0.91 | MAOA (0.38) | MAOBGPR84PROKR1FPR2CHKA | |
| SCHEMBL8971558 | 0.89 | CYP11B1 (0.36) | GPR84PROKR1FPR2CHKACYP11B1 | |
| SCHEMBL8971545 | 0.89 | CYP11B1 (0.36) | GPR84PROKR1FPR2CHKACYP11B1 | |
| SCHEMBL8451888 | 0.89 | MAOB (0.42) | MAOBSLC6A2SLC6A4SLC6A3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |