Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Testosterone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | SHBG | P04278 | 5/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 3/20 | 1.00 |
| ▸ | PGR | P06401 | 3/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 3/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | SNCA | P37840 | 2/20 | 1.00 |
| ▸ | CACNA1C | Q13936 | 2/20 | 1.00 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 1.00 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.73 |
| ▸ | ESR1 | P03372 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epitestosterone SCHEMBL14034478 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL617693 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Testosterone SCHEMBL145157 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL16305625 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL13752937 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL11588466 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL2678780 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL12367194 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL21957465 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 | |
| Epitestosterone SCHEMBL22704809 | 1.00 | AR (1.00) | ARLMNACYP3A4SHBGCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 146441 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146967-A1 | DEVICE AND SENSOR FOR DETECTION OF AN ANALYTE | REMINDED, INC. (US) | 2026-05-28 | — | — | US | claimed |
| EP-4747643-A1 | DEVICES AND METHODS FOR IMMUNOASSAY ANALYSIS OF BIOLOGICAL SAMPLES | Vital Biosciences Inc. (CA) | 2026-05-27 | — | — | EP | claimed |
| EP-4232021-B1 | SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES | UNIV PABLO DE OLAVIDE (ES) | 2026-05-27 | — | — | EP | claimed |
| CN-122081260-A | Nonspecific peroxidase CsaUPO, coding gene thereof, recombinant microorganism, steroid epoxidation method and application | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081205-A | Fertilization culture solution and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | claimed |
| CN-122081256-A | Application of ketoreductase mutant in catalyzing reduction reaction of steroid ketone compounds | — | 2026-05-26 | — | — | CN | claimed |
| CN-122095084-A | Antigen-specific T cell receptors and chimeric antigen receptors and methods of use in modulation of immune signaling for cancer immunotherapy | — | 2026-05-26 | — | — | CN | claimed |
| CN-122091250-A | Method and system for predicting ovulation-promoting period pregnancy ending of PCOS patient | — | 2026-05-26 | — | — | CN | claimed |
| CN-121081533-B | Cistanche fermentation liquor for improving energy and cell aging and preparation method thereof | 厦门元之道生物科技有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-4098647-A | Composition of matter and process | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | claimed |
| US-4097335-A | AEROBIC CULTIVATION OF MYCOBACTERIUM FORTIUTUM | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | claimed |
| US-4097586-A | Immunochemical assay method | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1978-06-27 | — | — | US | claimed |
| US-4085202-A | Testosterone derivatives | BECTON, DICKINSON AND COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4071623-A | ESTROGENICALLY ACTIVE STEROIDS | AKZONA INCORPORATED (US) | 1978-01-31 | — | — | US | claimed |
| US-4062729-A | Microbial transformation of steroids | THE UPJOHN COMPANY (US) | 1977-12-13 | — | — | US | claimed |
| US-4042459-A | CULTIVATING A STEROID FROM MYCOBACTERIUM | THE UPJOHN COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4039381-A | STEROIDS | THE UPJOHN COMPANY (US) | 1977-08-02 | — | — | US | claimed |
| US-3990956-A | Electrochemical reduction of α,β-unsaturated keto steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | claimed |
| US-3962430-A | Sterilization of solid non-electrolyte medicinal agents employing sodium chloride | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | claimed |