Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452201 | 1.00 | GPR84 (0.38) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8453469 | 0.93 | MAOB (0.39) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8453472 | 0.93 | MAOB (0.39) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8456014 | 0.92 | PROKR1 (0.35) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8456006 | 0.92 | PROKR1 (0.35) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8447705 | 0.91 | RARB (0.37) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8447708 | 0.91 | RARB (0.37) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8452649 | 0.90 | MAOB (0.39) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8452651 | 0.90 | MAOB (0.39) | GPR84PROKR1FPR2PDE4APDE4B | |
| SCHEMBL8451029 | 0.90 | GPR84 (0.38) | GPR84PRCPCYP11B1CYP11B2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |