Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.52 |
| ▸ | CNR1 | P21554 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605553 | 0.94 | CNR2 (0.58) | CNR2CNR1LMNANPC1RAB9A | |
| SCHEMBL4605163 | 0.94 | CNR2 (0.58) | CNR2CNR1LMNANPC1RAB9A | |
| SCHEMBL5274265 | 0.89 | CNR1 (0.56) | CNR2CNR1LMNANPC1RAB9A | |
| SCHEMBL4605679 | 0.87 | CNR1 (0.60) | CNR2CNR1LMNAMAPTCYP1A2 | |
| SCHEMBL4606201 | 0.87 | CNR1 (0.60) | CNR2CNR1LMNAMAPTCYP1A2 | |
| SCHEMBL4606979 | 0.86 | CNR1 (0.53) | CNR2CNR1 | |
| SCHEMBL8469991 | 0.86 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL4605885 | 0.85 | CNR1 (0.61) | CNR2CNR1LMNAMAPTCYP1A2 | |
| SCHEMBL4607380 | 0.83 | CNR1 (0.61) | CNR2CNR1NPC1RAB9AHPGD | |
| SCHEMBL2288238 | 0.83 | CNR1 (0.61) | CNR2CNR1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |