Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453089 | 1.00 | MAOA (0.39) | MAOAMAOBSPHK1CYP2C9ALDH1A1 | |
| SCHEMBL8452152 | 0.94 | MAOA (0.36) | MAOAMAOBSPHK1CYP2C9ALDH1A1 | |
| SCHEMBL8448501 | 0.94 | MAOA (0.36) | MAOAMAOBSPHK1CYP2C9ALDH1A1 | |
| SCHEMBL8448497 | 0.94 | MAOA (0.36) | MAOAMAOBSPHK1CYP2C9ALDH1A1 | |
| SCHEMBL8452155 | 0.94 | MAOA (0.36) | MAOAMAOBSPHK1CYP2C9ALDH1A1 | |
| SCHEMBL8451061 | 0.93 | SPHK1 (0.45) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8451057 | 0.93 | SPHK1 (0.45) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8451079 | 0.93 | SPHK1 (0.36) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8451081 | 0.93 | SPHK1 (0.36) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8857700 | 0.93 | CYP2C9 (0.45) | SPHK1CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |