SCHEMBL8453203

SCHEMBL8453203

CC(O)(O)C1CCC(c2cc(F)c(F)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8446856 0.85 PDE2A (0.33)
SCHEMBL12997531 0.80 CES2 (0.35)
SCHEMBL9763629 0.75 ESR2 (0.45)
SCHEMBL9763635 0.75 ESR2 (0.45)
SCHEMBL19159799 0.75 ESR2 (0.45)
SCHEMBL17827799 0.74 CES2 (0.31)
SCHEMBL14175184 0.72 CES2 (0.30)
SCHEMBL12917833 0.72 ESR2 (0.32) RIPK1
SCHEMBL8446776 0.71 ESR2 (0.54) MEN1KMT2ACYP3A4CYP2C9
SCHEMBL6159058 0.71 CYP2C9 (0.46) MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0647696-B1 Cyclohexane derivative CHISSO CORP (JP) 1999-04-21 EP disclosed
EP-0647696-A1 Cyclohexane derivative Chisso Corporation (JP) 1995-04-12 EP disclosed
US-5382379-A Cyclohexane derivative CHISSO CORPORATION (JP) 1995-01-17 US disclosed