SCHEMBL8453579

SCHEMBL8453579

CCCCCCCCCCC(O)[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.46
SPHK1 Q9NYA1 2/20 0.46
FFAR1 O14842 2/20 0.46
LMNA P02545 2/20 0.46
CYP2D6 P10635 2/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CETP P11597 1/20 0.43
HTT P42858 1/20 0.43
UBE2N P61088 1/20 0.43
SMPD1 P17405 3/20 0.42
FFAR4 Q5NUL3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3824544 1.00 GPR84 (0.46) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL31243285 1.00 GPR84 (0.46) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL20895865 1.00 GPR84 (0.46) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL8455563 0.97 GPR84 (0.43) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL5575497 0.81 GPR84 (0.43) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL5575256 0.81 GPR84 (0.43) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL5575373 0.80 GPR84 (0.46) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL29111953 0.80 GPR84 (0.46) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL20127160 0.79 GPR84 (0.42) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL3957807 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59042391-A None JP disclosed
EP-0630902-B1 Silanes containing hydrophilic groups, their preparation and use as surfactants in aqueous media GOLDSCHMIDT AG TH (DE) 1999-01-13 EP disclosed
US-5430167-A Silanes with hydrophilic groups, their synthesis and use as surfactants in aqueous media TH. GOLDSCHMIDT AG (DE) 1995-07-04 US disclosed
EP-0630902-A1 Silanes containing hydrophilic groups, their preparation and use as surfactants in aqueous media Th. Goldschmidt AG (DE) 1994-12-28 EP disclosed
JP-S5942391-A PREPARATION OF 1-SILYL-1-ALKANOL SAGAMI CHEM RES CENTER 1984-03-08 JP disclosed