Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453600 | 1.00 | FASN (0.44) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8453595 | 1.00 | FASN (0.44) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8451772 | 0.90 | CYP2C9 (0.41) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8455482 | 0.90 | CYP3A4 (0.40) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8451769 | 0.90 | CYP2C9 (0.41) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8451765 | 0.90 | CYP2C9 (0.41) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8455485 | 0.90 | CYP3A4 (0.40) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL8455476 | 0.90 | CYP3A4 (0.40) | FASNCYP3A4CYP2C9APPOPRL1 | |
| SCHEMBL15298462 | 0.90 | FASN (0.45) | FASNCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL8857786 | 0.89 | CYP2C9 (0.42) | FASNCYP3A4CYP2C9APPOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |