Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453632 | 1.00 | FFAR4 (0.35) | FFAR4HRH3P2RY14DRD2DRD3 | |
| SCHEMBL8452038 | 0.90 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL8452039 | 0.90 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL8450074 | 0.89 | DRD2 (0.32) | FFAR4DRD2DRD3 | |
| SCHEMBL8450078 | 0.89 | DRD2 (0.32) | FFAR4DRD2DRD3 | |
| SCHEMBL8453250 | 0.85 | HRH3 (0.31) | FFAR4HRH3P2RY14 | |
| SCHEMBL8453245 | 0.85 | HRH3 (0.31) | FFAR4HRH3P2RY14 | |
| SCHEMBL8398127 | 0.83 | SPHK1 (0.30) | SPHK1 | |
| SCHEMBL8398129 | 0.83 | SPHK1 (0.30) | SPHK1 | |
| SCHEMBL8449230 | 0.83 | DRD2 (0.30) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004478-A | LIQUID CRYSTAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0732335-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |