SCHEMBL8454445

SCHEMBL8454445

C=COC(=O)C(=CCC)CC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28171015 0.84 GRIK1 (0.36) ALDH1A1TSHRGRIK1GRIK2
SCHEMBL181359 0.83 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL27758286 0.78 TSHR (0.33) ALDH1A1TSHR
SCHEMBL3961508 0.77 CYP2D6 (0.31) ALDH1A1TSHR
SCHEMBL21810567 0.76 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL6535679 0.76 GRIK1 (0.34) ALDH1A1TSHRGRIK1GRIK2
SCHEMBL5331456 0.76 GRIK1 (0.35) ALDH1A1TSHRGRIK1GRIK2
SCHEMBL5331451 0.76 GRIK1 (0.35) ALDH1A1TSHRGRIK1GRIK2
SCHEMBL10062277 0.76 GRIK1 (0.35) ALDH1A1TSHRGRIK1GRIK2
SCHEMBL6044981 0.76 GRIK1 (0.35) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001505-A ELECTRODES IN CONTACT WITH A HEAT SEALED BAG MADE OF MALEIC ACID MODIFIED POLYOLEFIN, LEADS OF SPECIFIC METALS OR ALLOYS EXTEND OUTSIDE THE BAG; BAG SERVES AS BARRIER AGAINST NONAQUEOUS ELECTROLYTIC SOLUTION AND STEAM, HERMETIC SEALING SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1999-12-14 US disclosed
US-5160475-A Saponified ethylene-vinyl acetate, ethylene-propylen, graft polymer blend NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-11-03 US disclosed
CN-1053620-A The continuous processing of preparation resin particle in the liquid DU PONT (US) 1991-08-07 CN disclosed
CN-1037596-A Monofunctional amines is as the assistant of liquid electrostatic developer DU PONT (US) 1989-11-29 CN disclosed