Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8454595 | 1.00 | CYP3A4 (0.35) | CYP3A4CYP2C9PROKR1APPCYP11B1 | |
| SCHEMBL8447396 | 0.92 | MAOB (0.38) | PROKR1CYP11B1CYP11B2MAOBPTGES2 | |
| SCHEMBL8447399 | 0.92 | MAOB (0.38) | PROKR1CYP11B1CYP11B2MAOBPTGES2 | |
| SCHEMBL8450964 | 0.92 | CYP2C9 (0.35) | CYP3A4CYP2C9PROKR1APPCYP11B1 | |
| SCHEMBL8450968 | 0.92 | CYP2C9 (0.35) | CYP3A4CYP2C9PROKR1APPCYP11B1 | |
| SCHEMBL8447406 | 0.91 | CYP2C9 (0.35) | CYP3A4CYP2C9PROKR1APPCYP11B1 | |
| SCHEMBL8447403 | 0.91 | CYP2C9 (0.35) | CYP3A4CYP2C9PROKR1APPCYP11B1 | |
| SCHEMBL8451911 | 0.89 | CYP2C9 (0.34) | CYP3A4CYP2C9APPMAOBDGAT1 | |
| SCHEMBL8455996 | 0.89 | PTGES2 (0.39) | CYP3A4CYP2C9APPMAOBDGAT1 | |
| SCHEMBL8455992 | 0.89 | PTGES2 (0.39) | CYP3A4CYP2C9APPMAOBDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |