SCHEMBL8455372

SCHEMBL8455372

CCCCCCCCCCCCCCCCC(O)COCC(O)CNCCO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
USP2 O75604 1/20 0.44
PSMD14 O00487 2/20 0.40
PLA2G1B P04054 2/20 0.40
MMP2 P08253 2/20 0.40
ATG4B Q9Y4P1 2/20 0.40
HSP90AA1 P07900 1/20 0.40
RAD52 P43351 1/20 0.40
HTT P42858 2/20 0.39
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 1/20 0.38
GPR84 Q9NQS5 5/20 0.38
FFAR4 Q5NUL3 1/20 0.37
FFAR1 O14842 1/20 0.37
PLA2G2C Q5R387 1/20 0.35
LMNA P02545 2/20 0.35
LPAR5 Q9H1C0 1/20 0.35
CYP2D6 P10635 2/20 0.34
SPHK1 Q9NYA1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935312 0.90 USP2 (0.55) KDM4EUSP2PSMD14PLA2G1BMMP2
SCHEMBL1394274 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL28710310 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL964072 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL14995368 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL5032443 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL3142060 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL968428 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL965864 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B
SCHEMBL967065 0.87 PSMD14 (0.46) KDM4EPSMD14PLA2G1BMMP2ATG4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed