Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8455458 | 1.00 | DRD2 (0.46) | DRD2MAOBMAOASPHK1CYP2C9 | |
| SCHEMBL8454717 | 0.94 | DRD2 (0.48) | DRD2MAOBMAOASPHK1CYP2C9 | |
| SCHEMBL8454726 | 0.94 | DRD2 (0.48) | DRD2MAOBMAOASPHK1CYP2C9 | |
| SCHEMBL8448110 | 0.92 | SPHK1 (0.50) | DRD2MAOBSPHK1SPHK2 | |
| SCHEMBL8448108 | 0.92 | SPHK1 (0.50) | DRD2MAOBSPHK1SPHK2 | |
| SCHEMBL8451713 | 0.92 | MAOB (0.43) | DRD2MAOBMAOASPHK1CYP2C9 | |
| SCHEMBL8451722 | 0.92 | MAOB (0.43) | DRD2MAOBMAOASPHK1CYP2C9 | |
| SCHEMBL8456015 | 0.91 | MAOB (0.49) | DRD2MAOBMAOAALDH1A1KDM4E | |
| SCHEMBL8456020 | 0.91 | MAOB (0.49) | DRD2MAOBMAOAALDH1A1KDM4E | |
| SCHEMBL8447261 | 0.91 | SPHK1 (0.56) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |