Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8455964 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2KCNH2RARARARB | |
| SCHEMBL8447594 | 0.99 | SPHK1 (0.48) | SPHK1SPHK2KCNH2RARARARB | |
| SCHEMBL8447600 | 0.99 | SPHK1 (0.48) | SPHK1SPHK2KCNH2RARARARB | |
| SCHEMBL8452483 | 0.99 | SPHK1 (0.48) | SPHK1SPHK2KCNH2RARARARB | |
| SCHEMBL8452480 | 0.99 | SPHK1 (0.48) | SPHK1SPHK2KCNH2RARARARB | |
| SCHEMBL8456001 | 0.97 | SPHK1 (0.42) | SPHK1SPHK2 | |
| SCHEMBL8456005 | 0.97 | SPHK1 (0.42) | SPHK1SPHK2 | |
| SCHEMBL8453555 | 0.94 | KCNH2 (0.41) | SPHK1KCNH2RARARARBRARG | |
| SCHEMBL8453552 | 0.94 | KCNH2 (0.41) | SPHK1KCNH2RARARARBRARG | |
| SCHEMBL8452573 | 0.93 | DRD2 (0.38) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |