Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845404 | 0.96 | PREP (0.50) | PREPF10NPSR1TSHRL3MBTL1 | |
| SCHEMBL4385819 | 0.90 | GFER (0.58) | PREPF10NPSR1TSHRL3MBTL1 | |
| SCHEMBL10756717 | 0.84 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL10756725 | 0.84 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL489615 | 0.84 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL4386402 | 0.83 | GFER (0.58) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL7655851 | 0.83 | PREP (0.62) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL872323 | 0.82 | STAT6 (0.43) | F10L3MBTL1KDM4ELMNAALDH1A1 | |
| SCHEMBL25678350 | 0.80 | PREP (0.58) | PREPNPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL26364677 | 0.80 | PREP (0.59) | PREPNPSR1TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |