Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845652 | 0.82 | PREP (0.53) | L3MBTL1KDM4ELMNAF10ALDH1A1 | |
| SCHEMBL845404 | 0.79 | PREP (0.50) | STAT6L3MBTL1KDM4ELMNAF10 | |
| SCHEMBL20482408 | 0.79 | RAB9A (0.42) | L3MBTL1ACEACE2PRCPKDM4E | |
| SCHEMBL13573736 | 0.75 | RAB9A (0.49) | L3MBTL1ACEACE2PRCPKDM4E | |
| SCHEMBL695608 | 0.73 | RAB9A (0.62) | L3MBTL1ACEACE2MAPTKDM4E | |
| SCHEMBL2634067 | 0.73 | RAB9A (0.62) | L3MBTL1ACEACE2MAPTKDM4E | |
| SCHEMBL5493674 | 0.73 | RAB9A (0.62) | L3MBTL1ACEACE2MAPTKDM4E | |
| SCHEMBL695607 | 0.73 | FKBP1A (0.51) | L3MBTL1LMNARAB9ASMN1; SMN2FKBP1A | |
| SCHEMBL13272182 | 0.73 | LMNA (0.49) | L3MBTL1KDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL20482498 | 0.72 | L3MBTL1 (0.53) | L3MBTL1ACEACE2PRCPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| EP-1893573-B1 | INHIBITORS OF HCV REPLICATION | BRISTOL MYERS SQUIBB CO (US) | 2010-07-21 | — | — | EP | disclosed |