Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845254 | 1.00 | POLB (0.58) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL844855 | 1.00 | POLB (0.58) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL10119499 | 0.91 | POLB (0.50) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845529 | 0.90 | POLB (0.56) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845261 | 0.90 | POLB (0.56) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845487 | 0.90 | POLB (0.56) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845491 | 0.90 | POLB (0.55) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845133 | 0.88 | POLB (0.62) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL845132 | 0.87 | POLB (0.72) | POLBKDM4ELMNANPSR1KDM1A | |
| SCHEMBL844848 | 0.87 | POLB (0.72) | POLBKDM4ELMNANPSR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |