Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845357 | 1.00 | POLB (0.72) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845132 | 1.00 | POLB (0.72) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845133 | 0.91 | POLB (0.62) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845523 | 0.89 | POLB (0.59) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL4386483 | 0.88 | POLB (0.73) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL4383169 | 0.88 | POLB (0.76) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL12230365 | 0.88 | POLB (0.80) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845654 | 0.87 | POLB (0.59) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845136 | 0.87 | POLB (0.59) | POLBMEN1KMT2AKDM1ARCOR1 | |
| SCHEMBL845689 | 0.87 | POLB (0.58) | POLBMEN1KMT2AKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |