Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.87 |
| ▸ | PPARA | Q07869 | 9/20 | 0.87 |
| ▸ | PPARD | Q03181 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8457673 | 1.00 | PPARG (0.87) | PPARGPPARAPPARD | |
| SCHEMBL8457664 | 0.95 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL2789319 | 0.93 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2789322 | 0.93 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2787121 | 0.90 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2787118 | 0.90 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7923250 | 0.88 | PPARG (0.89) | PPARGPPARAPPARD | |
| SCHEMBL7923249 | 0.88 | PPARG (0.89) | PPARGPPARAPPARD | |
| SCHEMBL2788829 | 0.86 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2785147 | 0.86 | PPARG (1.00) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |