Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ACP3 | P15309 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950022 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP2C9CYP2C19CYP1A2HPGD | |
| SCHEMBL7924283 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL29957205 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL6005218 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL18242412 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL5949824 | 0.78 | PARP1 (0.39) | ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5236200 | 0.77 | CYP1A2 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2CYP2A6 | |
| SCHEMBL11444158 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL28192 | 0.76 | ALDH1A1 (0.74) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 | |
| SCHEMBL9669273 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP2C9CYP2C19CYP1A2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930621-A | Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119661534-A | Matrine aminothiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-119930621-A | Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119661534-A | Matrine aminothiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-03-21 | — | — | CN | disclosed |
| EP-2432774-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING URIC ACID LEVELS | Ardea Biosciences, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135530-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING URIC ACID LEVELS | ARDEA BIOSCIENCES, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | disclosed |
| EP-0871626-A1 | NOVEL TRIAZOLONES AS APOLIPOPROTEIN-B SYNTHESIS INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996033193-A1 | NOVEL TRIAZOLONES AS APOLIPOPROTEIN-B SYNTHESIS INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-10-24 | — | — | WO | disclosed |