Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARG | P13631 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458022 | 0.80 | PTPN11 (0.44) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL10686211 | 0.71 | KDM4E (0.50) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8458370 | 0.71 | RARB (0.51) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8458427 | 0.71 | RARB (0.51) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8457301 | 0.71 | RARB (0.51) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8458236 | 0.71 | RARB (0.51) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8459002 | 0.69 | RARB (0.48) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8459703 | 0.69 | RARB (0.52) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8458019 | 0.69 | PTPN11 (0.58) | RARBRARGRARAPTPN11CNR2 | |
| SCHEMBL8458437 | 0.67 | RARB (0.42) | RARBRARGRARAPTPN11CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | claimed |