Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.44 |
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979397 | 0.81 | RARB (0.55) | PTPN11PPARGPPARDPPARARARB | |
| SCHEMBL8458020 | 0.80 | CA9 (0.41) | PTPN11CNR2CNR1FAAHPPARG | |
| SCHEMBL8459709 | 0.79 | RARB (0.41) | PTPN11CNR2CNR1FAAHPPARG | |
| SCHEMBL8458437 | 0.78 | RARB (0.42) | PTPN11CNR2CNR1FAAHPPARG | |
| SCHEMBL8458019 | 0.77 | PTPN11 (0.58) | PTPN11CNR2CNR1FAAHRARB | |
| SCHEMBL8458380 | 0.76 | RARB (0.40) | PTPN11CNR2CNR1FAAHPPARG | |
| SCHEMBL8457312 | 0.76 | RARB (0.39) | PTPN11CNR2CNR1FAAHPPARG | |
| SCHEMBL7330160 | 0.73 | PTPN11 (0.56) | PTPN11PPARAMEN1NR1I2LMNA | |
| SCHEMBL9677245 | 0.73 | PTPN11 (0.56) | PTPN11PPARAMEN1NR1I2LMNA | |
| SCHEMBL9330868 | 0.73 | PTPN11 (0.56) | PTPN11PPARAMEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | claimed |