Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.40 |
| ▸ | RARA | P10276 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688833 | 1.00 | RXRA (0.40) | RXRARARARARBRARGCYP3A4 | |
| SCHEMBL8458065 | 1.00 | RXRA (0.40) | RXRARARARARBRARGCYP3A4 | |
| SCHEMBL4960820 | 0.87 | RXRA (0.52) | RXRARARARARBRARGPPARG | |
| SCHEMBL4960828 | 0.87 | RXRA (0.52) | RXRARARARARBRARGPPARG | |
| SCHEMBL8458066 | 0.86 | RXRA (0.34) | RXRARARARARBRARGCYP3A4 | |
| SCHEMBL8462265 | 0.72 | RXRA (0.45) | RXRARARARARBRARGPPARG | |
| SCHEMBL4959128 | 0.72 | RXRA (0.67) | RXRARARARARBRARGPPARG | |
| SCHEMBL6685049 | 0.71 | RXRA (0.51) | RXRACYP3A4KMT2APPARGNR1H3 | |
| SCHEMBL6675620 | 0.70 | RXRA (0.65) | RXRARARARARBRARGPPARG | |
| SCHEMBL8459590 | 0.69 | RXRA (0.45) | RXRARARARARBRARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958956-A | SKIN DISORDERS; WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5726191-A | TREATEMENT OF LIGHT AND AGE DAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |