Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458130 | 1.00 | ESR2 (0.34) | ESR2KDM1ARCOR1EPHX2JAK2 | |
| SCHEMBL8458127 | 1.00 | ESR2 (0.34) | ESR2KDM1ARCOR1EPHX2JAK2 | |
| SCHEMBL8454325 | 0.95 | KDM1A (0.33) | ESR2KDM1ARCOR1EPHX2JAK2 | |
| SCHEMBL8454328 | 0.95 | KDM1A (0.33) | ESR2KDM1ARCOR1EPHX2JAK2 | |
| SCHEMBL8454327 | 0.95 | KDM1A (0.33) | ESR2KDM1ARCOR1EPHX2JAK2 | |
| SCHEMBL8456683 | 0.94 | L3MBTL1 (0.36) | KDM1ARCOR1EPHX2JAK2JAK1 | |
| SCHEMBL8456680 | 0.94 | L3MBTL1 (0.36) | KDM1ARCOR1EPHX2JAK2JAK1 | |
| SCHEMBL8456674 | 0.94 | L3MBTL1 (0.36) | KDM1ARCOR1EPHX2JAK2JAK1 | |
| SCHEMBL8454281 | 0.92 | L3MBTL1 (0.35) | KDM1ARCOR1EPHX2JAK2JAK1 | |
| SCHEMBL8454273 | 0.92 | L3MBTL1 (0.35) | KDM1ARCOR1EPHX2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |