Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.65 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458250 | 1.00 | PPARG (0.65) | PPARGYAP1PPARA | |
| SCHEMBL7708321 | 0.88 | PPARG (0.84) | PPARG | |
| SCHEMBL7708314 | 0.88 | PPARG (0.84) | PPARG | |
| SCHEMBL7711546 | 0.87 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL7711541 | 0.87 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL2805642 | 0.81 | PPARG (1.00) | PPARGYAP1PPARA | |
| SCHEMBL9994772 | 0.81 | PPARG (1.00) | PPARG | |
| SCHEMBL2805640 | 0.81 | PPARG (1.00) | PPARGYAP1PPARA | |
| SCHEMBL9994771 | 0.81 | PPARG (1.00) | PPARG | |
| SCHEMBL2806311 | 0.77 | PPARG (1.00) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |