Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 1.00 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9994771 | 1.00 | PPARG (1.00) | PPARGGPR132GPR34MMEACE | |
| SCHEMBL7708321 | 0.92 | PPARG (0.84) | PPARGGPR132GPR34 | |
| SCHEMBL7708314 | 0.92 | PPARG (0.84) | PPARGGPR132GPR34 | |
| SCHEMBL7708319 | 0.84 | PPARG (0.72) | PPARGACE | |
| SCHEMBL8458245 | 0.81 | PPARG (0.65) | PPARG | |
| SCHEMBL8458250 | 0.81 | PPARG (0.65) | PPARG | |
| SCHEMBL2785014 | 0.79 | PPARG (0.88) | PPARG | |
| SCHEMBL2787967 | 0.78 | PPARG (0.67) | PPARGGPR34 | |
| SCHEMBL2786646 | 0.78 | PPARG (0.67) | PPARG | |
| SCHEMBL6182299 | 0.76 | GPR132 (0.77) | PPARGGPR132GPR34MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300129-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2011-12-08 | — | — | US | disclosed |