SCHEMBL845825

SCHEMBL845825

O=S(=O)(O)c1ccccc1P

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MYC P01106 1/20 0.44
TTR P02766 2/20 0.42
FABP4 P15090 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
MAPK14 Q16539 1/20 0.38
NR4A1 P22736 1/20 0.37
CA1 P00915 5/20 0.36
CA2 P00918 5/20 0.36
MMP1 P03956 3/20 0.36
MMP2 P08253 3/20 0.36
MMP9 P14780 3/20 0.36
MMP8 P22894 3/20 0.36
MMP13 P45452 3/20 0.36
PGAM1 P18669 1/20 0.36
CYP1A2 P05177 2/20 0.36
GAA P10253 2/20 0.36
CHAT P28329 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31021957 1.00 TSHR (0.44) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL7706296 0.98 MYC (0.42) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL28581245 0.98 MYC (0.42) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL27267455 0.98 MYC (0.42) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL4564632 0.95 MYC (0.41) TSHRSMN1; SMN2MYCTTRFABP4
Biphenyl SCHEMBL27380486 0.91 TSHR (0.43) TSHRSMN1; SMN2MYCTTRFABP4
Acetonitrile SCHEMBL17594987 0.88 MYC (0.41) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL2593808 0.82 PGAM1 (0.40) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL27477582 0.81 TTR (0.44) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL29664068 0.81 TSHR (0.55) TSHRSMN1; SMN2MYCTTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724951-A Phosphine-sulfonate compound having aralkyl group and method for producing metal complex using the same as ligand precursor 国立大学法人东京大学 2024-10-01 CN claimed
EP-2303903-B1 CLAY ACTIVATION OF PD(II) AND NI(II) COMPLEXES UNIV CALIFORNIA (US) 2016-11-16 EP claimed
CN-104058919-B A kind of method preparing 1-heptene SINOPEC CORP. (CN) 2016-03-30 CN claimed
CN-104447162-A Method for preparing dodecylene CHINA PETROLEUM & CHEMICAL 2015-03-25 CN claimed
US-8268946-B2 Clay activation of PD(II) and NI(II) complexes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-09-18 US claimed
JP-2011525211-A 2011-09-15 JP claimed
EP-2303903-A1 CLAY ACTIVATION OF PD(II) AND NI(II) COMPLEXES The Regents of the University of California (US) 2011-04-06 EP claimed
US-20090326174-A1 CLAY ACTIVATION OF PD(II) AND NI(II) COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-12-31 US claimed
WO-2009155509-A1 CLAY ACTIVATION OF PD(II) AND NI(II) COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-12-23 WO claimed
CN-1078496-C Galvano-chemistry prepn. method of catalyst on basis of transition metal and phosphine RHONE POULENC FIBRES (FR) 2002-01-30 CN claimed
CN-1045591-C Method for hydrocyanation of unsatured nitrile into dinitrile RHONE POULENC CHIMIE (FR) 1999-10-13 CN claimed
CN-1132503-A Method for preparing of mono or Di-2-substituted cyclopentanone RHONE POULENC AGROCHIMIE (FR) 1996-10-02 CN claimed
CN-1108643-A Method for hydrocyanation of unsatured nitrile into dinitrile RHONE POULENC CHIMIE (FR) 1995-09-20 CN claimed
CN-1021320-C PROCESS FOR CATALYTIC HYDROFORMYLATION OF OLEFINS ENIRICERCHE SPA (IT) 1993-06-23 CN claimed
CN-1044453-A The process for catalytic hydroformylation of alkene ENIRICERCHE SPA (IT) 1990-08-08 CN claimed
JP-2024145995-A METHOD FOR PRODUCING PHOSPHINE-SULFONATE ESTER COMPOUND WITH ARALKYL GROUP 国立大学法人 東京大学 2024-10-15 JP disclosed
CN-118724951-A Phosphine-sulfonate compound having aralkyl group and method for producing metal complex using the same as ligand precursor 国立大学法人东京大学 2024-10-01 CN disclosed
CN-1044453-A The process for catalytic hydroformylation of alkene ENIRICERCHE SPA (IT) 1990-08-08 CN disclosed
CN-1006064-B Process for the preparation of aldehydes 路埃西米股份公司 1989-12-13 CN disclosed
EP-0133410-A1 Process for preparing tri(M-sulphophenyl)phosphine RHONE-POULENC RECHERCHES (FR) 1985-02-20 EP disclosed