Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 20/20 | 0.58 |
| ▸ | HTR1B | P28222 | 9/20 | 0.57 |
| ▸ | HTR1D | P28221 | 9/20 | 0.57 |
| ▸ | HTR1A | P08908 | 8/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL7013309 | 0.91 | HTR1F (0.60) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7006117 | 0.80 | HTR1F (0.63) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7011191 | 0.78 | HTR1F (0.80) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| Lactic Acid SCHEMBL7007717 | 0.77 | HTR1F (0.61) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| Lactic Acid SCHEMBL30908955 | 0.77 | HTR1F (0.61) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7011890 | 0.76 | HTR1F (0.58) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL30909281 | 0.76 | HTR1F (0.58) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7006579 | 0.74 | HTR1F (1.00) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7005319 | 0.74 | HTR1F (0.79) | HTR1FHTR1BHTR1DHTR1AHTR2A | |
| SCHEMBL7005835 | 0.74 | HTR1F (0.82) | HTR1FHTR1BHTR1DHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998622-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | ELI LILLY AND COMPANY (US) | 1999-12-07 | — | — | US | disclosed |