Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461164 | 1.00 | EBP (0.32) | EBPSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL8459836 | 0.78 | CYP3A4 (0.31) | CYP3A4CYP2D6 | |
| SCHEMBL8459059 | 0.69 | CYP3A4 (0.31) | CYP3A4CYP2D6 | |
| SCHEMBL8458386 | 0.65 | — | — | |
| SCHEMBL8460474 | 0.64 | CYP3A4 (0.30) | CYP3A4CYP2D6 | |
| SCHEMBL34465344 | 0.59 | ALDH1A1 (0.40) | CYP3A4 | |
| SCHEMBL22499776 | 0.59 | TSHR (0.45) | CYP3A4 | |
| SCHEMBL10439946 | 0.59 | TSHR (0.45) | CYP3A4 | |
| SCHEMBL10825927 | 0.59 | TSHR (0.45) | CYP3A4 | |
| SCHEMBL27468392 | 0.59 | TSHR (0.45) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886177-A | ETHYLENE GLYCOL MONOMERS JOINED VIA STANDARD PHOSPHATE LINKAGES INCLUDING PHOSPHOROTHIOATE, PHOSPHODIESTER, AND PHOSPHORAMIDATE LINKAGES; USEFUL FUNCTIONAL GROUPS INCLUDE NUCLEOBASES AS WELL AS POLAR GROUPS, HYDROPHOBIC GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |