Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365639 | 0.82 | PPARG (0.43) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL20755515 | 0.80 | PPARG (0.44) | PPARGPPARAFFAR1 | |
| SCHEMBL131888 | 0.79 | PPARG (0.55) | PPARGPPARAFFAR1 | |
| SCHEMBL27785130 | 0.79 | PPARG (0.43) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL131889 | 0.78 | PPARG (0.45) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL1523584 | 0.78 | PPARG (0.43) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL10366694 | 0.77 | MAOB (0.47) | PPARGPPARAFFAR1 | |
| SCHEMBL10364895 | 0.76 | PPARG (0.46) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL10366899 | 0.74 | PPARG (0.44) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL10365461 | 0.72 | HPGD (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999059586-A1 | THIAZOLIDINE AND OXAZOLIDINE DERIVATIVES FOR THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION AND INHIBITION OF CARDIOMYOCYTE APOPTOSIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-25 | — | — | WO | claimed |