SCHEMBL8458778

SCHEMBL8458778

CC(C)(C)c1cccc(NC(=O)c2ccc(C(=O)O)cc2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.78
HDAC6 Q9UBN7 2/20 0.78
HDAC3 O15379 1/20 0.78
KCNK9 Q9NPC2 2/20 0.73
NR1H4 Q96RI1 8/20 0.63
KCNK3 O14649 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 2/20 0.59
RAB9A P51151 2/20 0.59
KMT2A Q03164 2/20 0.59
TP53 P04637 1/20 0.59
THRB P10828 1/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
NFKB1 P19838 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
CA1 P00915 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12266428 0.91 KCNK9 (0.82) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL2301778 0.89 HDAC8 (0.63) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL14195814 0.88 KCNK9 (0.83) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL15603524 0.88 HDAC8 (0.78) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL9978818 0.87 HDAC6 (0.77) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL15603559 0.87 HDAC8 (0.76) HDAC8HDAC6HDAC3KCNK9KCNK3
SCHEMBL21652165 0.87 HDAC8 (0.76) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL21652183 0.87 HDAC8 (0.76) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL8462152 0.87 HDAC6 (0.77) HDAC8HDAC6HDAC3KCNK9NR1H4
SCHEMBL25669613 0.87 HDAC8 (0.81) HDAC8HDAC6HDAC3KCNK9NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12489131-B2 Compositions for energy conversion and storage and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-12-02 US disclosed
CN-120053875-A Electrochemical oxygen therapy patch and preparation method and application thereof 中国科学技术大学 2025-05-30 CN disclosed
US-20240322226-A1 Si-SUBSTITUTED LITHIUM THIOBORATE MATERIAL WITH HIGH LITHIUM ION CONDUCTIVITY FOR USE AS SOLID-STATE ELECTROLYTE AND ELECTRODE ADDITIVE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-09-26 US disclosed
CN-118553938-A Anti-poisoning fuel cell anode catalyst, preparation method thereof and fuel cell 嘉庚创新实验室 2024-08-27 CN disclosed
US-20240154154-A1 Si-SUBSTITUTED LITHIUM THIOBORATE MATERIAL WITH HIGH LITHIUM ION CONDUCTIVITY FOR USE AS SOLID-STATE ELECTROLYTE AND ELECTRODE ADDITIVE CALIFORNIA INST OF TECHN (US) 2024-05-09 US disclosed
US-20240117472-A1 NICKEL-BASE ALLOY ATI PROPERTIES LLC 2024-04-11 US disclosed
CN-117118522-B Ultra-narrow line width wide-tuning millimeter wave output device and working method 中国矿业大学 2024-03-12 CN disclosed
CN-114420944-B Fuel cell membrane electrode, preparation method thereof and fuel cell 一汽解放汽车有限公司 2024-02-23 CN disclosed
WO-2023235559-A1 SI-SUBSTITUTED LITHIUM THIOBORATE MATERIAL WITH HIGH LITHIUM ION CONDUCTIVITY FOR USE AS SOLID-STATE ELECTROLYTE AND ELECTRODE ADDITIVE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-12-07 WO disclosed
CN-117118522-A Ultra-narrow line width wide-tuning millimeter wave output device and working method 中国矿业大学 2023-11-24 CN disclosed
CN-114978332-A Millimeter wave signal generating device and method with tunable frequency and phase 中国矿业大学 2022-08-30 CN disclosed
CN-113171789-B Metallic ruthenium monatomic catalyst for catalyzing hydrochlorination of acetylene and preparation method and application thereof 石河子大学 2022-08-09 CN disclosed
CN-114630857-A Method for producing polyepoxysazanes and for producing aminofunctional polyorganosiloxanes using polyepoxysazanes 美国陶氏有机硅公司 2022-06-14 CN disclosed
CN-114420944-A Fuel cell membrane electrode, preparation method thereof and fuel cell 一汽解放汽车有限公司 2022-04-29 CN disclosed
CN-114292406-A Preparation method of wrinkling cylinder sticking agent 江苏富淼科技股份有限公司 2022-04-08 CN disclosed
CN-114031781-A Modified polyamide epoxy copolymer and application thereof 江苏富淼科技股份有限公司 2022-02-11 CN disclosed
WO-1999048529-A1 RETINOID-GLITAZONE COMBINATIONS WARNER-LAMBERT COMPANY (US) 1999-09-30 WO disclosed
EP-0808159-A1 USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) WARNER-LAMBERT COMPANY (US) 1997-11-26 EP disclosed
WO-1996024344-A1 USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) WARNER-LAMBERT COMPANY (US) 1996-08-15 WO disclosed
US-5489611-A ADMINISTERING A RETINOID COMPOUND WARNER-LAMBERT COMPANY (US) 1996-02-06 US disclosed