Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458238 | 0.92 | KMT2A (0.44) | LMNASMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL8459004 | 0.91 | MEN1 (0.43) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8459777 | 0.90 | MEN1 (0.44) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8455746 | 0.90 | ALOX5AP (0.43) | LMNAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8457496 | 0.89 | KMT2A (0.41) | LMNASMN1; SMN2CNR2MAPTPOLB | |
| SCHEMBL8457981 | 0.89 | ALOX5AP (0.44) | LMNAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8457462 | 0.85 | HIF1A (0.47) | LMNACNR2FAAHCNR1MAPT | |
| SCHEMBL8457121 | 0.84 | RARA (0.53) | LMNAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL7920651 | 0.81 | RARB (0.54) | LMNASMN1; SMN2CNR2FAAHCNR1 | |
| SCHEMBL7521122 | 0.81 | MEN1 (0.61) | LMNASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |