Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL6869811 | 1.00 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL6378989 | 1.00 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL16527654 | 0.96 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL81366 | 0.96 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL25339362 | 0.92 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL20528134 | 0.92 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL22443056 | 0.92 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL22128148 | 0.92 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL1434088 | 0.92 | TSHR (0.44) | TSHRLMNACA4OR51E2CYP3A4 | |
| Cadaverine Tartrate SCHEMBL11837346 | 0.92 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711246-B1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECH INC (US) | 2012-03-28 | — | — | EP | claimed |
| US-7594957-B2 | Method of absorbing oxygen | MULTISORB TECHNOLOGIES, INC. (US) | 2009-09-29 | — | — | US | claimed |
| EP-1711246-A4 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECH INC (US) | 2008-07-30 | — | — | EP | claimed |
| US-20070007490-A1 | METHOD OF ABSORBING OXYGEN | MULTISORB TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | claimed |
| US-7125498-B2 | Oxygen-absorbing compositions and method | MULTISORB TECHNOLOGIES, INC. (US) | 2006-10-24 | — | — | US | claimed |
| EP-1711246-A1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | Multisorb Technologies, Inc. (US) | 2006-10-18 | — | — | EP | claimed |
| WO-2005077494-A1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECHNOLOGIES, INC. (US) | 2005-08-25 | — | — | WO | claimed |
| US-20050166755-A1 | Oxygen-absorbing compositions and method | MULTISORB TECHNOLOGIES, INC. | 2005-08-04 | — | — | US | claimed |
| CN-104556426-A | Preparation method for phosphorus-free compound corrosion and scale inhibitor | WUHU XIECHENG METAL PRODUCTS CO LTD | 2015-04-29 | — | — | CN | disclosed |
| EP-1711246-B1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECH INC (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7594957-B2 | Method of absorbing oxygen | MULTISORB TECHNOLOGIES, INC. (US) | 2009-09-29 | — | — | US | disclosed |
| EP-1711246-A4 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECH INC (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20070007490-A1 | METHOD OF ABSORBING OXYGEN | MULTISORB TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20070003672-A1 | Tri-part calcium fortified compositions and methods of making the same | COCO-COLA COMPANY | 2007-01-04 | — | — | US | disclosed |
| US-20070003671-A1 | Two-part calcium fortified compositions and methods of making the same | COCO-COLA COMPANY | 2007-01-04 | — | — | US | disclosed |
| US-7125498-B2 | Oxygen-absorbing compositions and method | MULTISORB TECHNOLOGIES, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1711246-A1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | Multisorb Technologies, Inc. (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005077494-A1 | OXYGEN-ABSORBING COMPOSITIONS AND METHOD | MULTISORB TECHNOLOGIES, INC. (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20050166755-A1 | Oxygen-absorbing compositions and method | MULTISORB TECHNOLOGIES, INC. | 2005-08-04 | — | — | US | disclosed |